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Phosphorylation of Human Insulin Receptor Substrate-1 at Serine 629 Plays a Positive Role in Insulin Signaling

The function of insulin receptor substrate-1 (IRS-1) is regulated by both tyrosine and serine/threonine phosphorylation. Phosphorylation of some serine/threonine residues in IRS-1 dampens insulin signaling, whereas phosphorylation of other serine/threonine residues enhances insulin signaling. Phosph...

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Detalhes bibliográficos
Main Authors: Luo, Moulun, Langlais, Paul, Yi, Zhengping, Lefort, Natalie, De Filippis, Elena A., Hwang, Hyonson, Christ-Roberts, Christine Y., Mandarino, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581341/
https://ncbi.nlm.nih.gov/pubmed/17640984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0049
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