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Label-free Relative Quantification of Co-eluting Isobaric Phosphopeptides of Insulin Receptor Substrate-1 by HPLC-ESI-MS/MS

Intracellular signal transduction is often regulated by transient protein phosphorylation in response to external stimuli. Insulin signaling is dependent on specific protein phosphorylation events, and analysis of insulin receptor substrate-1 (IRS-1) phosphorylation reveals a complex interplay betwe...

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Hlavní autoři: Langlais, Paul, Mandarino, Lawrence J., Yi, Zhengping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995262/
https://ncbi.nlm.nih.gov/pubmed/20594869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2010.05.009
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