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Phosphoprotein abundance changes in hypertensive cardiac remodeling

There is over-whelming evidence that protein phosphorylations regulate cardiac function and remodeling. A wide variety of protein kinases, e.g., phosphoinositide 3-kinase (PI3K), Akt, GSK-3, TGFβ, and PKA, MAPKs, PKC, Erks, and Jaks, as well as phosphatases, e.g., phosphatase I (PP1) and calcineurin...

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Autors principals: Kotlo, Kumar, Johnson, Keven R., Grillon, Jean M., Geenen, David L., deTombe, Pieter, Danziger, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581302/
https://ncbi.nlm.nih.gov/pubmed/22659219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.05.041
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