Φορτώνει......
Transcriptional Reprogramming of Mature CD4(+) T helper Cells generates distinct MHC class II-restricted Cytotoxic T Lymphocytes
TCRαβ thymocytes differentiate to either CD8αβ cytotoxic T lymphocytes or CD4(+) T helper cells. This functional dichotomy is controlled by key transcription factors, including the T helper master regulator, ThPOK, which suppresses the cytolytic program in MHC class II-restricted CD4(+) thymocytes....
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581083/ https://ncbi.nlm.nih.gov/pubmed/23334788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2523 |
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