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Isolation of novel prototype galectins from the marine ball sponge Cinachyrella sp. guided by their modulatory activity on mammalian glutamate-gated ion channels

Here we report the bioactivity-guided isolation of novel galectins from the marine sponge Cinachyrella sp., collected from Iriomote Island, Japan. The lectin proteins, which we refer to as the Cinachyrella galectins (CchGs), were identified as the active principles in an aqueous sponge extract that...

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Main Authors: Ueda, Takuya, Nakamura, Yuka, Smith, Caleb M, Copits, Bryan A, Inoue, Akira, Ojima, Takao, Matsunaga, Satoko, Swanson, Geoffrey T, Sakai, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581077/
https://ncbi.nlm.nih.gov/pubmed/23213112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws165
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