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Isolation of novel prototype galectins from the marine ball sponge Cinachyrella sp. guided by their modulatory activity on mammalian glutamate-gated ion channels

Here we report the bioactivity-guided isolation of novel galectins from the marine sponge Cinachyrella sp., collected from Iriomote Island, Japan. The lectin proteins, which we refer to as the Cinachyrella galectins (CchGs), were identified as the active principles in an aqueous sponge extract that...

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Hlavní autoři: Ueda, Takuya, Nakamura, Yuka, Smith, Caleb M, Copits, Bryan A, Inoue, Akira, Ojima, Takao, Matsunaga, Satoko, Swanson, Geoffrey T, Sakai, Ryuichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581077/
https://ncbi.nlm.nih.gov/pubmed/23213112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws165
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