Novel N-Methylated 8-Oxoisoguanines from Pacific Sponges with Diverse Neuroactivities

Marine organisms have yielded a variety of metabolites with neuropharmacological applications. Here we describe the isolation and pharmacological characterization of four novel, neurologically active purines 1–4, isolated from Haplosclerida sponges collected in the Republic of Palau. The structures...

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Hlavní autoři: Sakurada, Tsuyoshi, Gill, Martin B., Frausto, Shanti, Copits, Bryan, Noguchi, Keiichi, Shimamoto, Keiko, Swanson, Geoffrey T., Sakai, Ryuichi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241477/
https://ncbi.nlm.nih.gov/pubmed/20681583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100490m
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