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Genome maintenance and transcription integrity in aging and disease
DNA damage contributes to cancer development and aging. Congenital syndromes that affect DNA repair processes are characterized by cancer susceptibility, developmental defects, and accelerated aging (Schumacher et al., 2008). DNA damage interferes with DNA metabolism by blocking replication and tran...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580961/ https://ncbi.nlm.nih.gov/pubmed/23443494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00019 |
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