Promising Noninvasive Cellular Phenotype in Prostate Cancer Cells Knockdown of Matrix Metalloproteinase 9

Cell surface interaction of CD44 and MMP9 increases migration and invasion of PC3 cells. We show here that stable knockdown of MMP9 in PC3 cells switches CD44 isoform expression from CD44s to CD44v6 which is more glycosylated. These cells showed highly adhesive morphology with extensive cell spreadi...

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Библиографические подробности
Главные авторы: Gupta, Aditi, Cao, Wei, Sadashivaiah, Kavitha, Chen, Wantao, Schneider, Abraham, Chellaiah, Meenakshi A.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580924/
https://ncbi.nlm.nih.gov/pubmed/23476138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/493689
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