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Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases

Glutamate is the primary excitatory amino acid neurotransmitter in the CNS. The concentration of glutamate in the synaptic cleft is tightly controlled by interplay between glutamate release and glutamate clearance. Abnormal glutamate release and/or dysfunction of glutamate clearance can cause overst...

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Detalhes bibliográficos
Main Authors: Lin, Chien-Liang Glenn, Kong, Qiongman, Cuny, Gregory D, Glicksman, Marcie A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580837/
https://ncbi.nlm.nih.gov/pubmed/22924507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.122
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