Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized open-label controlled trial

INTRODUCTION: Meropenem bactericidal activity depends on the time when the free drug concentrations remain above the minimum inhibitory concentration of pathogens. The goal of this study was to compare clinical and bacteriological efficacy of continuous meropenem infusion versus bolus administration...

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Hauptverfasser: Chytra, Ivan, Stepan, Martin, Benes, Jan, Pelnar, Petr, Zidkova, Alexandra, Bergerova, Tamara, Pradl, Richard, Kasal, Eduard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580671/
https://ncbi.nlm.nih.gov/pubmed/22742765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11405
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