Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized open-label controlled trial

INTRODUCTION: Meropenem bactericidal activity depends on the time when the free drug concentrations remain above the minimum inhibitory concentration of pathogens. The goal of this study was to compare clinical and bacteriological efficacy of continuous meropenem infusion versus bolus administration...

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Autores principales: Chytra, Ivan, Stepan, Martin, Benes, Jan, Pelnar, Petr, Zidkova, Alexandra, Bergerova, Tamara, Pradl, Richard, Kasal, Eduard
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580671/
https://ncbi.nlm.nih.gov/pubmed/22742765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11405
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