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Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized open-label controlled trial

INTRODUCTION: Meropenem bactericidal activity depends on the time when the free drug concentrations remain above the minimum inhibitory concentration of pathogens. The goal of this study was to compare clinical and bacteriological efficacy of continuous meropenem infusion versus bolus administration...

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Bibliografiske detaljer
Main Authors: Chytra, Ivan, Stepan, Martin, Benes, Jan, Pelnar, Petr, Zidkova, Alexandra, Bergerova, Tamara, Pradl, Richard, Kasal, Eduard
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580671/
https://ncbi.nlm.nih.gov/pubmed/22742765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11405
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