The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis

INTRODUCTION: X-linked adrenoleukodystrophy (X-ALD) is a complex disorder with variable expressivity that affects the nervous, adrenocortical and male reproductive systems. Although ABCD1 mutations are known to provide the genetic basis for X-ALD, its pathogenesis is not fully elucidated. While elev...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wang, Xiao-Ming, Yik, Wing Yan, Zhang, Peilin, Lu, Wange, Dranchak, Patricia K, Shibata, Darryl, Steinberg, Steven J, Hacia, Joseph G
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580430/
https://ncbi.nlm.nih.gov/pubmed/23036268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt130
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky