Modeling Considerations for (11)C-CUMI-101, an Agonist Radiotracer for Imaging Serotonin 1A Receptor In Vivo with PET

Several lines of evidence demonstrate involvement of serotonin 1A receptors (5-HT(1A)Rs) in the pathophysiology of neuropsychiatric disorders such as depression, suicidal behavior, schizophrenia, and Alzheimer’s disease. We recently published the synthesis and initial evaluation of [O-methyl-(11)C]2...

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Bibliographische Detailangaben
Hauptverfasser: Milak, Matthew S., Severance, Alin J., Ogden, R. Todd, Prabhakaran, Jaya, Kumar, J.S. Dileep, Majo, Vattoly J., Mann, J. John, Parsey, Ramin V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580231/
https://ncbi.nlm.nih.gov/pubmed/18344443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.107.046540
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