In vivo serotonin-sensitive binding of [(11)C]CUMI-101: a serotonin 1A receptor agonist positron emission tomography radiotracer

Positron emission tomography studies of 5-hydroxytryptamine (5-HT)(1A) receptors have hitherto been limited to antagonist radiotracers. Antagonists do not distinguish high/low-affinity conformations of G protein-coupled receptors and are less likely to be sensitive to intrasynaptic serotonin levels....

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Dettagli Bibliografici
Autori principali: Milak, Matthew S, Severance, Alin J, Prabhakaran, Jaya, Kumar, J S Dileep, Majo, Vattoly J, Ogden, R Todd, Mann, J John, Parsey, Ramin V
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049488/
https://ncbi.nlm.nih.gov/pubmed/20571518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.83
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