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In vivo serotonin-sensitive binding of [(11)C]CUMI-101: a serotonin 1A receptor agonist positron emission tomography radiotracer
Positron emission tomography studies of 5-hydroxytryptamine (5-HT)(1A) receptors have hitherto been limited to antagonist radiotracers. Antagonists do not distinguish high/low-affinity conformations of G protein-coupled receptors and are less likely to be sensitive to intrasynaptic serotonin levels....
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049488/ https://ncbi.nlm.nih.gov/pubmed/20571518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.83 |
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