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Mechanistic Analysis of the Contributions of DNA and Protein Damage to Radiation-Induced Cell Death

Protein oxidation can contribute to radiation-induced cell death by two mechanisms: (1) by reducing the fidelity of DNA repair, and (2) by decreasing cell viability directly. Previously, we explored the first mechanism by developing a mathematical model and applying it to data on Deinococcus radiodu...

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Detalhes bibliográficos
Main Authors: Shuryak, Igor, Brenner, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580191/
https://ncbi.nlm.nih.gov/pubmed/22663149
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