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Alkynoate Synthesis via Vinylogous Reactivity of Rh(II) Carbenoids

A new rhodium carbenoid approach to access alkynoates has been developed. This transformation combines the addition of enol ethers at the vinylogous position of β-siloxy-substituted vinyldiazo derivatives and an unprecedented siloxy group migration to yield the products as single diastereomers.

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Detalhes bibliográficos
Main Authors: Valette, Damien, Lian, Yajing, Haydek, John P., Hardcastle, Kenneth I., Davies, Huw M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580044/
https://ncbi.nlm.nih.gov/pubmed/22807172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201204047
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