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Calculation of Hydrodynamic Properties for G-Quadruplex Nucleic Acid Structures from in silico Bead Models

Nucleic acids enriched in guanine bases can adopt unique quadruple helical tertiary structures known as G-quadruplexes. G-quadruplexes have emerged as attractive drug targets as many G-quadruplex-forming sequences have been discovered in functionally critical sites within the human genome, including...

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Библиографические подробности
Главные авторы: Le, Huy T., Buscaglia, Robert, Dean, William L., Chaires, Jonathan B., Trent, John O.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580009/
https://ncbi.nlm.nih.gov/pubmed/22886555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/128_2012_351
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