MEPE-Derived ASARM Peptide Inhibits Odontogenic Differentiation of Dental Pulp Stem Cells and Impairs Mineralization in Tooth Models of X-Linked Hypophosphatemia

Mutations in PHEX (phosphate-regulating gene with homologies to endopeptidases on the X-chromosome) cause X-linked familial hypophosphatemic rickets (XLH), a disorder having severe bone and tooth dentin mineralization defects. The absence of functional PHEX leads to abnormal accumulation of ASARM (a...

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Xehetasun bibliografikoak
Egile Nagusiak: Salmon, Benjamin, Bardet, Claire, Khaddam, Mayssam, Naji, Jiar, Coyac, Benjamin R., Baroukh, Brigitte, Letourneur, Franck, Lesieur, Julie, Decup, Franck, Le Denmat, Dominique, Nicoletti, Antonino, Poliard, Anne, Rowe, Peter S., Huet, Eric, Vital, Sibylle Opsahl, Linglart, Agnès, McKee, Marc D., Chaussain, Catherine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579870/
https://ncbi.nlm.nih.gov/pubmed/23451077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056749
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