Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma

BACKGROUND: Palmitoylethanolamide (PEA) is an endogenous fatty acid amide displaying anti-inflammatory and analgesic actions. Moreover, several data have suggested that PEA reduced inflammation and tissue injury associated with spinal cord trauma and showed a regulatory role for peroxisome prolifera...

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Autores principales: Paterniti, Irene, Impellizzeri, Daniela, Crupi, Rosalia, Morabito, Rossana, Campolo, Michela, Esposito, Emanuela, Cuzzocrea, Salvatore
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579707/
https://ncbi.nlm.nih.gov/pubmed/23374874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-20
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