Novel Polymorphisms Associated with Tacrolimus Trough Concentrations: Results from a Multicenter Kidney Transplant Consortium

BACKGROUND: The CYP4503A5*1 genotype is associated with lower tacrolimus concentrations. Although its effect is important, it incompletely explains the variability in tacrolimus concentrations and has a relatively low minor allele frequency in Caucasians relative to African Americans (AA). METHODS:...

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Hlavní autoři: Jacobson, Pamala A., Oetting, William S., Brearley, Ann M, Leduc, Robert, Guan, Weihau, Schladt, David, Matas, Arthur J., Lamba, Vishal, Julian, Bruce A., Mannon, Rosalyn B., Israni, Ajay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579501/
https://ncbi.nlm.nih.gov/pubmed/21206424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318200e991
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