Peptidyl-prolyl cis/trans-Isomerase A1 (Pin1) Is a Target for Modification by Lipid Electrophiles

[Image: see text] Oxidation of membrane phospholipids is associated with inflammation, neurodegenerative disease, and cancer. Oxyradical damage to phospholipids results in the production of reactive aldehydes that adduct proteins and modulate their function. 4-Hydroxynonenal (HNE), a common product...

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Bibliografiske detaljer
Main Authors: Aluise, Christopher D., Rose, Kristie, Boiani, Mariana, Reyzer, Michelle L., Manna, Joseph D., Tallman, Keri, Porter, Ned A., Marnett, Lawrence J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2012
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579456/
https://ncbi.nlm.nih.gov/pubmed/23231502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300449g
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