Caspase Induction and BCL2 Inhibition in Human Adipose Tissue: A potential relationship with insulin signaling alteration

OBJECTIVE: Cell death determines the onset of obesity and associated insulin resistance. Here, we analyze the relationship among obesity, adipose tissue apoptosis, and insulin signaling. RESEARCH DESIGN AND METHODS: The expression levels of initiator (CASP8/9) and effector (CASP3/7) caspases as well...

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Detalhes bibliográficos
Main Authors: Tinahones, Francisco José, Coín Aragüez, Leticia, Murri, Mora, Oliva Olivera, Wilfredo, Mayas Torres, María Dolores, Barbarroja, Nuria, Gomez Huelgas, Ricardo, Malagón, Maria M., El Bekay, Rajaa
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579349/
https://ncbi.nlm.nih.gov/pubmed/23193206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-0194
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