Potent vasorelaxant activity of the TMEM16A inhibitor T16A(inh)-A01

BACKGROUND AND PURPOSE: T16A(inh)-A01 is a recently identified inhibitor of the calcium-activated chloride channel TMEM16A. The aim of this study was to test the efficacy of T16A(inh)-A01 for inhibition of calcium-activated chloride channels in vascular smooth muscle and consequent effects on vascul...

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Hauptverfasser: Davis, Alison J, Shi, Jian, Pritchard, Harry AT, Chadha, Preet S, Leblanc, Normand, Vasilikostas, Georgios, Yao, Zhen, Verkman, AS, Albert, Anthony P, Greenwood, Iain A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579294/
https://ncbi.nlm.nih.gov/pubmed/22946562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02199.x
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