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Population pharmacokinetics of unbound mycophenolic acid in adult allogeneic haematopoietic cell transplantation: effect of pharmacogenetic factors

AIM: To evaluate pharmacogenetic factors as contributors to the variability of unbound mycophenolic acid (MPA) exposure in adult allogeneic haematopoietic cell transplantation (alloHCT) recipients. METHODS: A population-based pharmacokinetic (PK) model of unbound MPA was developed using non-linear m...

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Autors principals: Frymoyer, Adam, Verotta, Davide, Jacobson, Pamala, Long-Boyle, Janel
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579261/
https://ncbi.nlm.nih.gov/pubmed/22765258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04372.x
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