Erythropoietin Neuroprotection in Neonatal Cardiac Surgery: A Phase I/II Safety and Efficacy Trial

OBJECTIVES: Neonates undergoing complex congenital heart surgery have a significant incidence of neurological problems. Erythropoietin has anti-apoptotic, anti-excitatory, and anti-inflammatory properties to prevent neuronal cell death in animal models, and improves neurodevelopmental outcomes in fu...

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Hauptverfasser: Andropoulos, Dean B., Brady, Ken, Easley, R. Blaine, Dickerson, Heather A., Voigt, Robert G., Shekerdemian, Lara S., Meador, Marcie R., Eisenman, Carol A., Hunter, Jill V., Turcich, Marie, Rivera, Carlos, McKenzie, E. Dean, Heinle, Jeffrey S., Fraser, Charles D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579008/
https://ncbi.nlm.nih.gov/pubmed/23102686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.09.046
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