Erythropoietin Neuroprotection in Neonatal Cardiac Surgery: A Phase I/II Safety and Efficacy Trial

OBJECTIVES: Neonates undergoing complex congenital heart surgery have a significant incidence of neurological problems. Erythropoietin has anti-apoptotic, anti-excitatory, and anti-inflammatory properties to prevent neuronal cell death in animal models, and improves neurodevelopmental outcomes in fu...

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Detalhes bibliográficos
Main Authors: Andropoulos, Dean B., Brady, Ken, Easley, R. Blaine, Dickerson, Heather A., Voigt, Robert G., Shekerdemian, Lara S., Meador, Marcie R., Eisenman, Carol A., Hunter, Jill V., Turcich, Marie, Rivera, Carlos, McKenzie, E. Dean, Heinle, Jeffrey S., Fraser, Charles D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579008/
https://ncbi.nlm.nih.gov/pubmed/23102686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.09.046
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