Follistatin-like 3 (FSTL3) Mediated Silencing of Transforming Growth Factor β (TGFβ) Signaling Is Essential for Testicular Aging and Regulating Testis Size

Follistatin-like 3 (FSTL3) is a glycoprotein that binds and inhibits the action of TGFβ ligands such as activin. The roles played by FSTL3 and activin signaling in organ development and homeostasis are not fully understood. The authors show mice deficient in FSTL3 develop markedly enlarged testes th...

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Autori principali: Oldknow, Karla J., Seebacher, Jan, Goswami, Tapasree, Villen, Judit, Pitsillides, Andrew A., O'Shaughnessy, Peter J., Gygi, Steven P., Schneyer, Alan L., Mukherjee, Abir
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2013
Soggetti:
Reproduction-Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578998/
https://ncbi.nlm.nih.gov/pubmed/23407452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1886
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