Follistatin-like 3 (FSTL3) Mediated Silencing of Transforming Growth Factor β (TGFβ) Signaling Is Essential for Testicular Aging and Regulating Testis Size

Follistatin-like 3 (FSTL3) is a glycoprotein that binds and inhibits the action of TGFβ ligands such as activin. The roles played by FSTL3 and activin signaling in organ development and homeostasis are not fully understood. The authors show mice deficient in FSTL3 develop markedly enlarged testes th...

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Autors principals: Oldknow, Karla J., Seebacher, Jan, Goswami, Tapasree, Villen, Judit, Pitsillides, Andrew A., O'Shaughnessy, Peter J., Gygi, Steven P., Schneyer, Alan L., Mukherjee, Abir
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2013
Matèries:
Reproduction-Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578998/
https://ncbi.nlm.nih.gov/pubmed/23407452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1886
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