Rab6a/a’ Are Important Golgi Regulators of Pro-Inflammatory TNF Secretion in Macrophages

Lipopolysaccharide (LPS)-activated macrophages secrete pro-inflammatory cytokines, including tumor necrosis factor (TNF) to elicit innate immune responses. Secretion of these cytokines is also a major contributing factor in chronic inflammatory disease. In previous studies we have begun to elucidate...

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Bibliographic Details
Main Authors: Micaroni, Massimo, Stanley, Amanda C., Khromykh, Tatiana, Venturato, Juliana, Wong, Colin X. F., Lim, Jet P., Marsh, Brad J., Storrie, Brian, Gleeson, Paul A., Stow, Jennifer L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578815/
https://ncbi.nlm.nih.gov/pubmed/23437303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057034
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