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Electron Tomography Reveals Rab6 Is Essential to the Trafficking of trans-Golgi Clathrin and COPI-Coated Vesicles and the Maintenance of Golgi Cisternal Number

We have shown previously that Rab6, a small, trans-Golgi-localized GTPase, acts upstream of the COG and ZW10/RINT1 retrograde tether complexes to maintain Golgi homeostasis. Here, we present evidence from the unbiased and high-resolution approach of electron microscopy and electron tomography that R...

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Detalhes bibliográficos
Main Authors: Storrie, Brian, Micaroni, Massimo, Morgan, Garry P., Jones, Nick, Kamykowski, Jeffrey A., Wilkins, Ngozi, Pan, Timothy H., Marsh, Brad J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324626/
https://ncbi.nlm.nih.gov/pubmed/22335553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2012.01343.x
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