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Role of Epigenetics in Chronic Myeloid Leukemia

The efficacy of therapeutic modalities in chronic myeloid leukemia (CML) depends on both genetic and epigenetic mechanisms. This review focuses on epigenetic mechanisms involved in the pathogenesis of CML and in resistance of tumor cells to tyrosine kinase inhibitors leading to the leukemic clone es...

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Detalhes bibliográficos
Main Authors: Machova Polakova, Katerina, Koblihova, Jitka, Stopka, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: Current Science Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578734/
https://ncbi.nlm.nih.gov/pubmed/23296408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11899-012-0152-z
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