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Role of Epigenetics in Chronic Myeloid Leukemia

The efficacy of therapeutic modalities in chronic myeloid leukemia (CML) depends on both genetic and epigenetic mechanisms. This review focuses on epigenetic mechanisms involved in the pathogenesis of CML and in resistance of tumor cells to tyrosine kinase inhibitors leading to the leukemic clone es...

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Bibliografiske detaljer
Main Authors: Machova Polakova, Katerina, Koblihova, Jitka, Stopka, Tomas
Format: Artigo
Sprog:Inglês
Udgivet: Current Science Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578734/
https://ncbi.nlm.nih.gov/pubmed/23296408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11899-012-0152-z
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