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Farnesoid X Receptor Protects Hepatocytes From Injury by Repressing miR-199a-3p, Which Increases Levels of LKB1

BACKGROUND & AIMS: Hepatocyte injury occurs during liver fibrogenesis. MicroRNAs (miRNA) regulate some of these processes, and some are regulated by the farnesoid X receptor (FXR). We investigated the effect of repression of specific miRNAs by FXR in hepatocyte injury using fibrotic liver tissue...

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Bibliografiske detaljer
Main Authors: LEE, CHAN GYU, KIM, YOUNG WOO, KIM, EUN HYUN, MENG, ZHIPENG, HUANG, WENDONG, HWANG, SE JIN, KIM, SANG GEON
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578415/
https://ncbi.nlm.nih.gov/pubmed/22265968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.01.007
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