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Enantioselective Total Synthesis of (+)-Reserpine

[Image: see text] A catalytic, enantioselective synthesis of (+)-reserpine is reported. The route features a highly diastereoselective, chiral catalyst-controlled formal aza-Diels–Alder reaction between a 6-methoxytryptamine-derived dihydro-β-carboline and an enantioenriched α-substituted enone to f...

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Detalhes bibliográficos
Main Authors: Rajapaksa, Naomi S., McGowan, Meredeth A., Rienzo, Matthew, Jacobsen, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578295/
https://ncbi.nlm.nih.gov/pubmed/23331099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol400046n
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