Corticosteroid insensitivity of chemokine expression in airway smooth muscle of patients with severe asthma

BACKGROUND: Patients with severe asthma are less responsive to the beneficial effects of corticosteroid therapy. OBJECTIVE: We investigated whether corticosteroid insensitivity was present in airway smooth muscle cells (ASMCs) of patients with severe asthma. METHODS: ASMCs cultured from bronchial bi...

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Bibliographic Details
Main Authors: Chang, Po-Jui, Bhavsar, Pankaj K., Michaeloudes, Charalambos, Khorasani, Nadia, Chung, Kian Fan
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578224/
https://ncbi.nlm.nih.gov/pubmed/22947346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.07.017
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