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TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells

Reactive oxygen species (ROS) are generated as a result of normal cellular metabolism, mainly through the mitochondria and peroxisomes, but their release is enhanced by the activation of oxidant enzymes such as NADPH oxidases or downregulation of endogenous antioxidant enzymes such as manganese-supe...

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Detalhes bibliográficos
Main Authors: Michaeloudes, Charalambos, Sukkar, Maria B., Khorasani, Nadia M., Bhavsar, Pankaj K., Chung, Kian Fan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043811/
https://ncbi.nlm.nih.gov/pubmed/21131394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00134.2010
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