Anti-tumor Effect of Paclitaxel is Mediated by Inhibition of MDSCs and Chronic Inflammation in the Spontaneous Melanoma Model

The anti-tumor effects of paclitaxel are generally attributed to the suppression of microtubule dynamics resulting in defects in cell division. New data demonstrated that in ultra-low non-cytotoxic concentrations, paclitaxel modulated in immune cells in vitro the activity of small Rho GTPases, the k...

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Bibliografiske detaljer
Main Authors: Sevko, Alexandra, Michels, Tillmann, Vrohlings, Melissa, Umansky, Ludmila, Beckhove, Philipp, Kato, Masashi, Shurin, Galina V., Shurin, Michael R., Umansky, Viktor
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578135/
https://ncbi.nlm.nih.gov/pubmed/23359505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202781
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