Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

Tumor microenvironment is characterized by chronic inflammation represented by infiltrating leukocytes and soluble mediators, which lead to a local and systemic immunosuppression associated with cancer progression. Here, we used the ret transgenic spontaneous murine melanoma model that mimics human...

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Detalhes bibliográficos
Main Authors: Meyer, Christiane, Sevko, Alexandra, Ramacher, Marcel, Bazhin, Alexandr V., Falk, Christine S., Osen, Wolfram, Borrello, Ivan, Kato, Masashi, Schadendorf, Dirk, Baniyash, Michal, Umansky, Viktor
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193202/
https://ncbi.nlm.nih.gov/pubmed/21969559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108121108
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