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Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models

Epoxy-fatty acids have been recognized as important cell signaling molecules with multiple biological effects including anti-nociception. The main degradation pathway of these signaling molecules is via the soluble epoxide hydrolase (sEH) enzyme. Inhibitors of sEH extend the anti-nociceptive effects...

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Main Authors: Wagner, Karen, Inceoglu, Bora, Dong, Hua, Yang, Jun, Hwang, Sung Hee, Jones, Paul, Morisseau, Christophe, Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578047/
https://ncbi.nlm.nih.gov/pubmed/23276668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.12.015
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