Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer

Two major populations of myeloid-derived suppressor cells (MDSC), monocytic MDSC (M-MDSC) and polymorphonuclear MDSC (PMN-MDSC) regulate immune responses in cancer and other pathologic conditions. Under physiologic conditions, Ly6C(hi)Ly6G(−) inflammatory monocytes, which are the normal counterpart...

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Détails bibliographiques
Auteurs principaux: Youn, Je-In, Kumar, Vinit, Collazo, Michelle, Nefedova, Yulia, Condamine, Thomas, Cheng, Pingyan, Villagra, Alejandro, Antonia, Scott, McCaffrey, Judith C., Fishman, Mayer, Sarnaik, Amod, Horna, Pedro, Sotomayor, Eduardo, Gabrilovich, Dmitry I.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578019/
https://ncbi.nlm.nih.gov/pubmed/23354483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2526
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