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Ammonia Inhibits Long-term Potentiation via Neurosteroid Synthesis in Hippocampal Pyramidal Neurons

Neurosteroids are a class of endogenous steroids synthesized in the brain that are believed to be involved in the pathogenesis of neuropsychiatric disorders and memory impairment. Ammonia impairs long-term potentiation (LTP), a synaptic model of learning, in the hippocampus, a brain region involved...

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Bibliographic Details
Main Authors: Izumi, Yukitoshi, Svrakic, Neda, O’Dell, Kazuko, Zorumski, Charles F.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578010/
https://ncbi.nlm.nih.gov/pubmed/23276672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.12.035
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