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Identification of Flavone Glucuronide Isomers by Metal Complexation and Tandem Mass Spectrometry: Regioselectivity of UDP-Glucuronosyltransferase Isozymes in the Biotransformation of Flavones

Flavone Glucuronide isomers of five flavones (chrysin, apigenin, luteolin, baicalein, and scutellarein) were differentiated by collision induced dissociation (CID) of [Co(II) (flavone-H) (4,7-diphenyl-1,10-phenanthroline)(2)](+) complexes. The complexes were generated via post-column addition of a m...

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Detalhes bibliográficos
Main Authors: Robotham, Scott A., Brodbelt, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578006/
https://ncbi.nlm.nih.gov/pubmed/23362992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jf304853j
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