Improved Detection of Remote Homologues Using Cascade PSI-BLAST: Influence of Neighbouring Protein Families on Sequence Coverage

BACKGROUND: Development of sensitive sequence search procedures for the detection of distant relationships between proteins at superfamily/fold level is still a big challenge. The intermediate sequence search approach is the most frequently employed manner of identifying remote homologues effectivel...

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Bibliografiska uppgifter
Huvudupphovsmän: Kaushik, Swati, Mutt, Eshita, Chellappan, Ajithavalli, Sankaran, Sandhya, Srinivasan, Narayanaswamy, Sowdhamini, Ramanathan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577913/
https://ncbi.nlm.nih.gov/pubmed/23437136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056449
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