Gene- and Protein-Delivered Zinc Finger–Staphylococcal Nuclease Hybrid for Inhibition of DNA Replication of Human Papillomavirus

Previously, we reported that artificial zinc-finger proteins (AZPs) inhibited virus DNA replication in planta and in mammalian cells by blocking binding of a viral replication protein to its replication origin. However, the replication mechanisms of viruses of interest need to be disentangled for th...

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Bibliographic Details
Main Authors: Mino, Takashi, Mori, Tomoaki, Aoyama, Yasuhiro, Sera, Takashi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577882/
https://ncbi.nlm.nih.gov/pubmed/23437192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056633
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