Calreticulin Induces Dilated Cardiomyopathy

BACKGROUND: Calreticulin, a Ca(2+)-buffering chaperone of the endoplasmic reticulum, is highly expressed in the embryonic heart and is essential for cardiac development. After birth, the calreticulin gene is sharply down regulated in the heart, and thus, adult hearts have negligible levels of calret...

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Detalhes bibliográficos
Main Authors: Lee, Dukgyu, Oka, Tatsujiro, Hunter, Beth, Robinson, Alison, Papp, Sylvia, Nakamura, Kimitoshi, Srisakuldee, Wattamon, Nickel, Barbara E., Light, Peter E., Dyck, Jason R. B., Lopaschuk, Gary D., Kardami, Elissavet, Opas, Michal, Michalak, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577809/
https://ncbi.nlm.nih.gov/pubmed/23437120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056387
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