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Calreticulin Induces Dilated Cardiomyopathy
BACKGROUND: Calreticulin, a Ca(2+)-buffering chaperone of the endoplasmic reticulum, is highly expressed in the embryonic heart and is essential for cardiac development. After birth, the calreticulin gene is sharply down regulated in the heart, and thus, adult hearts have negligible levels of calret...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577809/ https://ncbi.nlm.nih.gov/pubmed/23437120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056387 |
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