Changes in Muscle Cell Metabolism and Mechanotransduction Are Associated with Myopathic Phenotype in a Mouse Model of Collagen VI Deficiency

This study identifies metabolic and protein phenotypic alterations in gastrocnemius, tibialis anterior and diaphragm muscles of Col6a1(−/−) mice, a model of human collagen VI myopathies. All three muscles of Col6a1(−/−) mice show some common changes in proteins involved in metabolism, resulting in d...

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Autores principales: De Palma, Sara, Leone, Roberta, Grumati, Paolo, Vasso, Michele, Polishchuk, Roman, Capitanio, Daniele, Braghetta, Paola, Bernardi, Paolo, Bonaldo, Paolo, Gelfi, Cecilia
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577731/
https://ncbi.nlm.nih.gov/pubmed/23437220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056716
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