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Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance

The progressive elucidation of the molecular pathogenesis of cancer has fueled the rational development of targeted drugs for patient populations stratified by genetic characteristics. Here we discuss general challenges relating to molecular diagnostics and describe predictive biomarkers for persona...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gonzalez de Castro, D, Clarke, P A, Al-Lazikani, B, Workman, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577635/
https://ncbi.nlm.nih.gov/pubmed/23361103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.237
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