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Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance

The progressive elucidation of the molecular pathogenesis of cancer has fueled the rational development of targeted drugs for patient populations stratified by genetic characteristics. Here we discuss general challenges relating to molecular diagnostics and describe predictive biomarkers for persona...

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Autori principali: Gonzalez de Castro, D, Clarke, P A, Al-Lazikani, B, Workman, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577635/
https://ncbi.nlm.nih.gov/pubmed/23361103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.237
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