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Coupled mutation finder: A new entropy-based method quantifying phylogenetic noise for the detection of compensatory mutations

BACKGROUND: The detection of significant compensatory mutation signals in multiple sequence alignments (MSAs) is often complicated by noise. A challenging problem in bioinformatics is remains the separation of significant signals between two or more non-conserved residue sites from the phylogenetic...

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Detalhes bibliográficos
Main Authors: Gültas, Mehmet, Haubrock, Martin, Tüysüz, Nesrin, Waack, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577461/
https://ncbi.nlm.nih.gov/pubmed/22963049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-225
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